Journal of Genetic Medicine : eISSN 2383-8442 / pISSN 1226-1769

Fig. 2.

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Fig. 2.

The fluorescence in situ hybridization was performed with a hybrid probe for RAI1 locus at 17p11.2 (green) and PA-FAH1B1 (LIS1) gene at 17p13.3 (red) (Case 2). Two duplication RAI1 signals (green) were observed in a metaphase cell (left). In interphase cell, duplication RAI1 signals (green) were more prominently visualized in chromatin before condensed (left). While there are 2 LIS signals as a normal control (red), there is one more RAI1 signal (left).

Journal of Genetic Medicine 2019;16:49-54
© 2019 Korean Society of Medical Genetics and Genomics