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Partial molar pregnancy and coexisting fetus with Turner syndrome: Case report and literature review
J Genet Med 2018;15:43-47
Published online June 30, 2018;  https://doi.org/10.5734/JGM.2018.15.1.43
© 2018 Korean Society of Medical Genetics and Genomics.

Ji Eun Park1, Ji Kwon Park1,*, In Ae Cho2, and Jong Chul Baek1

1Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea
2Department of Obstetrics and Gynecology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea
Ji Kwon Park, M.D., Ph.D. http://orcid.org/0000-0002-9731-190X
Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, 11 Samjeongja-ro, Seongsan-gu, Changwon 51472, Korea.
Tel: +82-55-214-3780, Fax: +82-55-214-3253, E-mail: obgypjk@gnu.ac.kr
Received February 21, 2018; Revised March 25, 2018; Accepted March 26, 2018.
cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Partial hydatidiform mole and coexisting fetus is a rare entity with antecedent high risk of maternal and fetal complications, and risk of persistent trophoblastic disease in later life. Here, we report a case of twin pregnancy with live fetus identified as 45,X and normal placenta and another partial mole. Ultrasound scan at 10 weeks showed a hydrops fetus with a focal area of multicystic placenta. The patient underwent chorionic villus sampling and amniocentesis for chromosomal analysis, and the result was 45,X. Based on these finding, the patient then underwent induced abortion. Pathological examination (immunohistochemical staining) of the placenta confirmed the partial mole. This report suggests that careful prenatal ultrasonography and appropriate karyotyping in a molar pregnancy and coexisting fetus enable early diagnosis and may be beneficial for prognosis.
Keywords : Hydatidiform mole, Twins, Ultrasonography, Karyotyping.


June 2018, 15 (1)
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